Capsule filling using nozzle dosators (ND) has been widely investigated (Jones, 2001; Newton, 2012) and it is one of the main technologies used by pharmaceutical industry today. Nozzles come in sizes that match the diameter of capsules (from 00 to 5), and deliver a specific volume of powder into capsules. However, the amount of powder that the smallest nozzle (size 5) can handle is in the range of 40 mg-80 mg (depending on the density of the powder formulation).

This paper discusses the methodology for the development and scale up of capsule filling operations using a research capsule filling unit (Labby,MG2) and an industrial capsule filling machine (Planeta,MG2).

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Working and Principle of Tablet Coating Machine

Different Types of Machinery for Uniform Coating in Pharmaceutical Industries

Commonly used solid dosage forms include powders, granules, tablets, capsules, pills, films, etc.

A tablet press is used to compress pharmaceutical powder formulations into tablet form, creating tablets of uniform size, shape and weight.

The crusher industry is still a new industry in China, which belongs to the initial stage of development. However, from the experience of a few decades, the speed is relatively fast, especially the universal crusher. Its application field is expanding continuously, and it is suitable for pharmaceutical, chemical, metallurgical, food, construction and other industries.

Use of belt dryer is very wide, present in the pharmaceutical, food, biological, chemical and other fields already have it handy. However, in each area of its selection criteria is not the same, because the requirements and parameters of the dried material in various fields have a greater difference.

Although the belt dryer is relatively energy efficient dryer, but in practice there is a failure, and we have done is to identify the cause of the fault to be eliminated, so that belt dryer best energy efficiency for us service.

Fluid bed dryers. The average consumer has most likely never even heard of them. But in the world of bulk processing, fluid bed dryers have established themselves as dependable and multi-functional processors; capable of completing a variety of critical tasks.

Freeze dryer and lyophilizer are synonymous names for the same equipment. A freeze dryer executes a water removal process typically used to preserve perishable materials, to extend shelf life or make the material more convenient for transport. Freeze dryers work by freezing the material, then reducing the pressure and adding heat to allow the frozen water in the material to sublimate.

Tablets are solid dosage forms usually containing active pharmaceutical ingredient and excipients in powder, crystalline or granular form with or without diluents which is prepared either by moulding or compression process. Tablets are the most widely used solid dosage forms because of their advantages and popularity increasing day by day. Tablet usually contains filler, diluents, binders, lubricants, glidants, disintegrants, antiadherent, colouring agents and flavouring agents as excipients.

Freeze dryer and lyophilizer are synonymous names for the same equipment. A freeze dryer executes a water removal process typically used to preserve perishable materials, to extend shelf life or make the material more convenient for transport. Freeze dryers work by freezing the material, then reducing the pressure and adding heat to allow the frozen water in the material to sublimate.

when the machine works normally for a long time, the parts that are in direct contact with the drug should be cleaned regularly. When the drug batch is changed or the time of withdrawal is long, the parts should be cleaned regularly.

The fully automatic capsule filling machine consists of an empty capsule discharge device, a capsule distribution device, a powder discharge device, a metering plate mechanism, a capsule filling and sealing mechanism, a box main drive mechanism, and an electrical electrical control system.

Tablets are solid preparations made of tablets or special-shaped tablets after evenly mixed with drugs and excipients. Because they are simple to take and easy to carry, the market size of tablets has been growing continuously in recent years. The management and treatment of these common diseases, frequently-occurring diseases and chronic diseases are closely related to the use of tablets.

Check the machine parts regularly, 1-2 times a month. The inspection items are whether the worm wheel, worm, bearing, pressing wheel, crankshaft, upper and lower rail guide and other moving parts rotate flexibly and wear. If any defect is found, it shall be repaired and used in time.

Pharmaceutical tablet press is good or bad has a most reason is determined by the punching machine, in a nutshell is the punching machine is the core of the tablet press device, whether any form of tablet press, such as tablet tablet machine, high speed tableting machine, double tablet machine, double tablet machine, circular piece of tablet press, candy tablet press, etc., all need to be aware of is the installation of punching die!

Capsule filling machine integrates machine, electricity and gas. It adopts micro-computer programmable controller, touch panel operation, frequency conversion speed regulation, equipped with electronic automatic counting device, which can automatically complete the capsule positioning, separation, filling, locking and other actions, reduce labor intensity, improve production efficiency, and meet the requirements of pharmaceutical hygiene.

Disassembly And Installation Of Main Parts Of Small Powder Tablet Press

There are many factors that affect the quality of the automatic capsule filling machine, among which the powder filling mechanism and the positions of the capsule turret are important factors. In the aspect of powder filling mechanism, the powder filling mechanism is mainly composed of 6 equal parts of intermittent rotary movement metering plate, 6 groups of axial movement punch rod (adjustable axial position) and powder screw automatic feeder.

The coating process of sugar-coated tablets is complex, time-consuming and prone to many problems, such as cracks, bare edges, hemp noodles, patches and so on. Sugar coating has gradually been replaced by film coating, the following is only the film coating problem.